http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-1433004-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27be5c4b2d5fd2545c623981353dec34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_178493211e0dd63887cf451f98e10b7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eae9a77223112dbb09ac6344a2367087 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-547 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 |
| filingDate | 1986-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1993-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f74a9f293ac19619b2570f8758f8a51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa81e2ff7848f1128660890098f2280c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a647778a9ee73f5b2d3d3ac94090f41d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_451f08680df7fa066719ae195942c8c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_315bd113a0df4f99e7ac04b0a48e13b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12d3f0863ae8d4605b7938a5bbaab217 |
| publicationDate | 1993-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-1433004-C |
| titleOfInvention | 3,3- di -tert-butyl -6- mrthyl -5- oxo-2,3,4,5-tetrahydro -1,2,4,3- lyambda 4 - -triazaphosphorinium chloride showing antiviral activity with respect to vesicular stomatitis virus |
| abstract | The invention relates to the chemistry of organophosphorus compounds, in particular in 3,3-di-tert-3,3-di-tert-butyl-6-methyl-5-oxo-2,3,4,5-tet4 rahydro-12 , 4.3-A-triazaphosphorinium chloride, which has antiviral activity and can be used in medicine. The aim is to provide a more active compound against the virus of vesicular stomatitis. The title compound was prepared from di-tert-butyl-amino-hydrazinophosphoric chloride and pyruvic acid in benzene or toluene while boiling for 1.5 hours. 92% yield. T.P. 180 ° C (decomposition). LD 5000 mg / kg. The present compound completely inhibits the reproduction of the virus of vesicular stomatitis in contrast to ribamidyl. 2 tab. |
| priorityDate | 1986-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.