| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_178493211e0dd63887cf451f98e10b7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0af12fa10e20a1d7825fbfa159ca653a |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-223 |
| filingDate |
1986-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af5fd18861195783c2ad59cbddcdcd7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2340fec5d8e2aa52b7b382f6ad2fc2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9f5c25f16426bfa59403f4514ac0ab5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_025c625cdfcfe022f97fe02d40dc3e16 |
| publicationDate |
1993-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-1363764-C |
| titleOfInvention |
N-2-fluorenesulfonyl-o-propionyl-threo-d,l-phenylserine ethyl ester showing antiviral activity with respect to echo 11 virus |
| abstract |
The invention relates to esters of substituted amino acids, in particular to ethyl ester M-2-fluorensulfonyl-0-propioNyl-threo-0, L-phenylserine (EPS), which may find application in medicine. The chain is the creation of new derivatives of this series it exhibits antiviral activity against ECHO virus G. The production of EPS is carried out from ethyl phosphate L-2-fluorensulfonyl-threo-0.1.-phen1llserine and propionic acid chloride with absolute chloroform upon boiling. Yield 93, 1%, mp 138-140 °; C. EFS is only active against ECHO P at a dose of 500 μg / mp and a therapeutic index of 2.);, -. | Mi 4 .. to @ s "-.1 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/LT-4663-B |
| priorityDate |
1986-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |