http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RS-54880-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d3f1bfec8ac94cca9554e3c17db5c6d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0066 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-30 |
| filingDate | 2012-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4acdaf988d09f161e8a734fbcc5c9e50 |
| publicationDate | 2016-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RS-54880-B1 |
| titleOfInvention | PROCEDURE FOR THE PRODUCTION OF INTERMEDIATE ESTETROL PRODUCTS |
| abstract | A process for preparing a compound of formula (I), wherein the method consists of reacting a compound of formula (II) with an acylating or silylating agent to produce a compound of formula (III), wherein P1 and P2 each independently represent a protecting group selected from R2-Si-R3R4, or R1CO-, wherein R1 is a group selected from C1-6alkyl or C3-6cycloalkyl, wherein each of the groups is optionally substituted by one or more substituents independently selected from fluoro or C1-4alkyl; R2, R3 and R4 are each independently a group selected from C1-6alkyl or phenyl, where each of these groups is optionally substituted with one or more substituents independently selected from fluoro or C1-4alkyl; b) reacting a compound of formula (III) in the presence of palladium acetate or palladium chloride to produce the compound of formula (IV); and c) reacting a compound of formula (IV) with a reducing agent to produce a compound of formula (I). The application contains 13 further claims. |
| priorityDate | 2011-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.