http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RS-54717-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36002650e924d3edaec88b4324ca7e83 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-0016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06 |
| filingDate | 2004-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3807354e504e2546a8fcf047707800f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25dc1a94845e92736e8b26b3e1a60401 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbb7055ecaa6f0a686beff99ed6e0429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7207c2fcd5770e11a2d61fc08c7fb50c |
| publicationDate | 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RS-54717-B1 |
| titleOfInvention | PROSTAGLANDIN NITRO OXIDERIVES |
| abstract | A compound of general formula (I) or pharmaceutically acceptable salts or stereoisomers thereof: RXY-ONO2 (I) wherein R is a prostaglandin residue of formula (II): gdesymbol - - - represents a free bond L is X is -O- or -S-, Y is a bivalent radical having the following meanings: a) straight or branched C1-C20 alkylene, which is optionally substituted by one or more substituents selected from the group consisting of: halogen atoms, hydroxy, -ONO2 or T, where T is -OC (O ) (C1-C10 alkyl) -ONO2 or -O (C1-C10 alkyl) -ONO2; - cycloalkylene with 5 to 7 carbon atoms on the cycloalkylene ring, wherein the ring is optionally substituted by side chains T1, where T1 is straight or branched C10 alkyl; b) c) where n is an integer from 0 to 20 and n1 is an integer from 1 to 20; d) where X1 = -OCO- or -COO- and R2 is H or CH3; Z is - ( CH) n1- or the bivalent radical defined above under b) n1 is defined above and n2 is an integer from 0 to 2; e) where: Y1 is -CH2-CH2- (CH2) n2-; or -CH = CH- (CH2) n2-; Z is - (CH) n1- or the bivalent radical defined above under b) n1, n2, R2 and X1 are defined above; f) where: n1 and R2 are defined above , R3 is H or -COCH3; provided that when Y is selected as the bivalent radical mentioned under b) -f), the -ONO2 group is attached to - (CH2) n1g) where X2 is -O- or -S-, n3 is an integer from 1 to 6 and R2 is defined above; h) where: n4 is an integer from 0 to 10; n5 is an integer from 1 to 10; R4, R5, R6, R7 are either the same or different, or are H or a straight or branched C 1 -C 4 alkyl group; wherein the -ONO 2 group is bound n5 as defined above; Y 2 is a heterocyclic saturated, unsaturated or aromatic 5 or 6-membered ring containing one or more heteroatoms selected as nitrogen, oxygen. sulfur, and was selected as the Application contains 14 more claims. |
| priorityDate | 2004-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.