| abstract |
A compound represented by formula (I), a pharmaceutically acceptable salt or hydrate thereof: wherein in formula (I) R represents a hydrogen atom or a C 1-6 alkyl group, A1, A2 and A 3, which may be the same or different, each represent itself a hydrogen atom, a halogen atom, a C1-6alkyl group or a C1-6 alkoxy group, X represents a C1-6 alkylene group, Y represents a covalent bond or a C1-6 alkylene group, Z represents a covalent bond or a C1-6 alkylene group, thus , which the C1-6 alkylene group may be substituted by an aryl group, W represents a covalent bond or an oxygen atom; iCy represents an aryl group or a pyridyl group, wherein the aryl group or pyridyl group may have one to three substituents which may be the same or different, selected from the group consisting of a halogen atom, a cyano group, a C1-6 alkyl group, a C1-6 alkoxy group, wherein the C 1-6 alkyl group or the C 1-6 alkoxy group may be substituted by from one to three halogen atoms, as well as a C 2-6 alkanoyl group; |