http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RS-52851-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 2010-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e29cb20895505cd1876a596fecc2a4d |
| publicationDate | 2013-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RS-52851-B |
| titleOfInvention | CYCLOPROPYL AMID DERIVATIVES AIMING THE HISTAMINE H3 RECEPTOR |
| abstract | Compound of formula I, or enantiomers or diastereomers thereof, or pharmaceutically acceptable salts of formula I, or enantiomers or diastereomers thereof, or mixtures thereof: wherein: R 1 is aryl, heteroaryl, -C 1 -C 6 alkyl-C 1 -C 3 alkoxy, -C 1 -C 6 alkyl- hydroxy, -C1-C6alkyl-C (= O) -NR11R12, -S (= O) 2NR11R12, heterocycle, cyano, haloalkyl, -C (= O) NR11R12, alkoxy, or halogen, R2 is C1-C6alkyl or C3- R3, R4, R5, R6, R7, R8, R9, and R10 are each independently selected from H and C1-C3alkyl; iR11 and R12 are each independently selected from H, -C1-C6alkyl, -C1-C3alkyl-C1-C3alkoxy, 5-membered heterocycloalkyl containing at least one heteroatom selected from O and N, 6-membered heterocycloalkyl containing at least one heteroatom selected from O and N, - (C1-C3alkyl) - (5-membered heteroaryl containing at least one heteroatom selected from O and N), - (C1-C3alkyl) - (6-membered heteroaryl containing at least one heteroatom selected from O and N) ), haloalkyl, or R 11, R 12 and the nitrogen to which they are attached combine to form a heterocycloalkyl selected from pyrrolidinyl, morpholinyl, piperidinyl, and piperazinyl, wherein said heterocycloalkyl is optionally substituted with at least one substituent selected from -C 1 -C 3 alkyl and -C 1 -C6alkyl-C1-C3alkoxy; and provided that: i) at least one of R 3, R 4, R 5, R 6, R 7, R 8, R 9, and R 10 is C 1 -C 3 alkyl, ii) formula I never R 1 is a -C (= O) NR 11 R 12 group meta-attached to phenyl, R2 is isopropyl, and R11 and R12 are H; iiii) formula I is not in the cis configuration on cyclopropane. The application contains 14 more claims. |
| priorityDate | 2009-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.