| abstract |
Peptides and their functionally equivalent derivatives, in saline or unsalted form, of the general formula L1-X1-X2-X3-X4, in which: L1 is H, or acyl, X1 and X3, which are the same or different, optionally N-alkylated and / or Ca-alkylated, are selected from Arg, Orn and Lys, optionally guanidinyls, and phenylalanine substituted in the mat or para position with an amine or guanidine group; X2 is selected from Aib, Ac3c, Ac4c, Ac5c and Ac6c, optionally N-alkylated, X4 is selected from Phe, h-Phe, Tyr, Trp, 1-Nal, 2-Nal, h-1-Nal, h-2 -Nal, Cha, Chg and Phg, optionally amidized and / or Cα-alkylated. The application contains 8 more claims. |