http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RS-52447-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b755982699e3ea5199d569ee5f5344c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 |
| filingDate | 2006-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bb671acf0fea07e3ffd206444d949fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1940534da4d4fbc2cd3700962a6a89b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3069fbbf4802dc0135fd0f6c5c6e4d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72c2ba8b48bab0a484864bc57234cf69 |
| publicationDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RS-52447-B |
| titleOfInvention | 8-SUBSTITUTED BENZOAZEPINS AS MODULATORS OF TOLL-LIKE RECEPTORS |
| abstract | Compound Formulas solvates, tautomers, and pharmaceutically acceptable salts thereof, characterized in that: Y may be R1, R3 and R4 each represent hydrogen; R2 is selected from the group consisting of H, OR6, NR6R7, C1-C6 alkyl, C2-C6alkenyl , C2-C6 alkynyl, C1-C6 heteroalkyl, C3-C6 cycloalkyl, C3-C6cycloalkenyl, heterocycloalkyl of 3 to 8 ring atoms, where one atom is selected from nitrogen, oxygen and sulfur, aryl selected from the group consisting of phenyl , biphenyl, 1,2,3,4-tetrahydronaphthyl and naphthyl and 5-7-membered heteroaryl, wherein said alkyl, alkenyl, alkynyl, heteroalkyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, aryl and heteroaryl are optionally substituted with one or more groups independently selected from C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, F, Cl, Br, I, CN, OR6, NR6R7, C (= O) R6, C (= O) OR6, OC (= O) R6, C (= O) NR6R7, (C1-C6alkyl) amino, CH3OCH2O-, R6OC (= O) CH = CH2-, NR6SO2R7, SR6 and SO2R6; where R5a, R5b, and R50 are each hydrogen; and R 6 and R 7 are independently selected from H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 heteroalkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 cycloalkenyl, heterocycloalkyl of 3 to 8 ring atoms, wherein one atom selected from nitrogen, oxygen and sulfur, an aryl selected from the group consisting of phenyl, biphenyl, 1,2,3,4-tetrahydronaphthyl and naphthyl and 5-7-membered heteroaryl, wherein alkyl, alkenyl, alkynyl are mentioned. heteroalkyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, aryl and heteroaryl optionally substituted by one or more groups independently selected from C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, F, Cl, Br, I, CN, OR6 , NR6R7, C (= O) R6, C (= O) OR6, OC (= O) R6, C (= O) NR6R7, (C1-C6 alky) amino, CH3OCH2O-, R6OC (= O) CH = CH2-, NR6SO2R7, SR6 and SO2R6, or R6 and R7 together with the atom to which they are attached form a saturated or partially unsaturated heterocyclic ring, wherein said heterocyclic ring is optionally substituted by one or more groups independently selected from C1-C6 alkyl. C2-C6 alkenyl, C 2-C6 alkenyl, F, Cl, Br, I, CN, 0R6, NR6R7, C (= O) R6, C (= O) OR6, OC (= O) R6, C (= O) NR6R7, (C1- C6 alkyl) amino, CH3OCH2O-, R6OC (= O) CH = CH2-, NR6SO2R7, SR6 and SO2R6. The application contains 14 more claims. |
| priorityDate | 2005-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.