http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RS-51962-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6572ff5df928fd17340eb2a8cb6d8502 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 |
filingDate | 2010-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9b15ed87f587a97ef3c71d0b76ceae0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8892aacc8c6323a4fe2c603e3d1fe957 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17c712689c4cbb8346249b2bd987b93c |
publicationDate | 2012-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RS-51962-B |
titleOfInvention | NEW PROCEDURE FOR THE SYNTHESIS OF IVABRADINE AND ITS ADDITIONAL SALTS WITH PHARMACEUTICALLY ACCEPTABLE ACID |
abstract | NEW PROCESS OF SYNTHESIS OF IVABRADIN AND ITS ADDITIONAL SALTS WITH PHARMACEUTICALLY ACCEPTABLE ACID. Process for the synthesis of a compound of formula (VII), in racemic or optically active form: wherein R represents a hydrogen atom or a methyl group, characterized in that the compound of formula (VIII): reacts with a compound of formula (IX), in racemic or optically active form , as the free base or salt: wherein R, as defined hereinbefore, in the presence of a transition metal salt or lanthanide, is in a solvent to give a compound of formula (X), in racemic or optically active form: which translates to a compound of formula (VII) by the action of a hydride donor agent. The application contains 11 more patent claims. |
priorityDate | 2009-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.