http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RS-51655-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
| filingDate | 2007-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f358b5a230b5ecb39e7fca344062756f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7d26e0b4ca79037e6bfb8aee02a8420 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a543ec1d0313bcf5297071b717642fda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34668cfee287a7577ae434d8229f0f2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16f17de0fb862bf4576327597d1da97a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26ef7e8b151e47e513ec3bdce15d2dc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b911a4e1793178a760f3a269a978ae0c |
| publicationDate | 2011-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RS-51655-B |
| titleOfInvention | Isoquinoline derivatives and isoquinolinone derivatives substituted by cycloalkylamine |
| abstract | In formula (I): R1 je H, OH yl NH2; R2jeR ', (C7-C8) alkyl, (C1-C6) alkylene-R', (C2-C6) alkenyl, (C2-C6) alkynyl, ( C1-C6) alkylene-O-R ', (C1-C6) alkylene-CH [R'] 2, (C1-C6) alkylene-C (O) -R ', (C1-C6) alkylene-C (O ) NH2, (C1-C6) alkylene-C (O) NH-R ', (C1-C6) alkylene-C (O) NH- (C1-C6) alkyl, (C1-C6) alkylene-C (O) N [(C1-C6) alkyl] 2, (C1-C6) alkylene-C (O) N [R '] 2; (C1-C6) alkylene-C (O) O- (C1-C6) alkyl, C (O) O- (C1-C6) alkyl, C (O) OR'C (O) (C1-C6) alkyl, C (O) R ', C (O) -NH- (C2-C6) alkenyl, C (O) -NH- (C2-C6) alkynyl, C (O) NH- (C1-C6) alkyl, C (O) NHR ', C (O) -NH (C1-C6) alkylene-R', C (O) N [(C1-C6) alkyl] R'C (O) N [(C1-C6) alkyl) 2, C (O) - (C1-C6) alkylene-R ', C (O) O (C1-C6) alkylene-R ', with R2 R2 (C1-C6) alkyl, pod uslovom da u datom alkyl ostatku najmanje jedan vodonic je supstituisan sa OH, OCH3, COOH, СООСН3, NH2, NHCH3, N (CH3) 2 , CONH2, CONHCH3, CON (CH3) 2, and R2 is je (C1-C4) alkylene, za, cycloalkyl, gde (C1-C4) alkylene formira drugu, or the like; , drugi, 4-8 člani R3 is jeH, halogen, (C1-C6) alkyl, (C1-C6) alkylene-R ', OH, OR ", NH2, NHR", NR "R" with NH-C (O) -R ", R4 jeH halogen, hydroxy, CN, (C1-C6) alkyl, R ', (C1-C6) alkylene-R'; R5 is jeH, halogen, CN, NO2, (C1-C6) alkyl, (C2-C6) alkenyl, R ', (C1-C6) alkylene- (C6-C10) aryl (C2-C6) alkenylene- (C6-C10) aryl, (C1-C6) alkylene- (C5-C10) heterociklil, CH (OH) - ( C1-C6) alkyl, NH2, NH-R ', NH-SO2H, NH-SO2- (C1-C6) alkyl, NH-SO2-R', NH-C (O) - (C1-C6) alkyl, NH -C (O) -R ', C (O) N [(C1-C6) alkyl] 2, C (O) OH, with C (O) O- (C1-C6) alkyl; od drugogH, R ', (C1-C8) alkyl, (C1-C6) alkylene-R', (C1-C6) alkylene-O- (C1-C6) alkyl, (C1-C6) alkylene-O-R ' , (C1-C6) alkylene-CH [R '] 2, (C1-C6) alkylene-C (O) -R', (C1-C6) alkylene-C (O) NH2, (C1-C6) alkylene- C (O) NH-R ', (C1-C6) alkylene-C (O) NH- (C1-C6) alkyl, (C1-C6) alkylene-C (O) N [(C1-C6) alkyl] 2 , (C1-C6) alkylene-C (O) N [R '] 2; (C1-C6) alkylene-C (O) O- (C1-C6) alkyl, C (O) O- (C1-C6) alkyl, C (O) OR 'C (O) (C1-C6) alkyl, C (O) R', C (O) NH- (C1-C6) alkyl, C (O) NHR ', C (O) N [(C1-C6) alkyl] R'C (O) N [(C1-C6) alkyl] 2, C (O) - (C1-C6) alkylene-R ', C (O) O (C1-C6 alkylene-R ', or R6, R6', zajedno sa N-ato mom za koji water vesicle, formiraju (C5-C10) heterocyclyl group; R7 is jeH, halogen, CN, NO2, (C1-C6) alkyl, O- (C1-C6) alkyl, (C2-C6) alkenyl, R ', (C2-C6) alkenylene- (C6-C10) aryl, (C1-C6) alkylene-R ', CH (OH) - (C1-C6) alkyl, NH2, NH-R', NH-SO2H, NH-SO2 - (C1-C6) alkyl, NH-SO2-R ', SO2-NH2, SO2-NHR', NH-C (O) - (C1-C6) alkyl, NH-C (O) -R ', C ( O) N [(C1-C6) alkyl] 2, C (O) OH, ylC (O) O- (C1-C6) alkyl; R8 je H, halogen yl (C1-C6) alkyl; 3, 4, m, je, 1, 2, 3, 4, 5, r je, 0, 1, 2, je je O (CH2) p, S (CH2) p, S (O) (CH2) p, SO2 (CH2) p is NH (CH 2) p, N (C 1 -C 6) alkyl- (CH 2) p, N (C 3 -C 6) cycloalkyl; N [CO (C1-C6) alkyl] - (CH2) pyl N [(C1-C3) alkylene-R '] - (CH2) p; p je 0, 1, 2, 3 to 4; C3-C8) cycloalkyl, (C5-C10) heterocyclyl, (C6-C10) aryl; R @ 3 'is (C3-C8) cycloalkyl, (C5-C10) heterocyclyl, (C6-C10) aryl, (C1-C6) alkyl, (C1-C6) alkylene-R', (C1-C6) alkylene-O - (C1-C6) alkyl, (C1-C6) alkylene-O-R ', with (C1-C6) alkylene-NRxRy; ) heterocyclyl, (C6-C10) aryl, (C1-C4) alkylen- (C5-C10) heterocycle |
| priorityDate | 2006-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 57.