| abstract |
Compounds of formula (I), (Ia) and (Ib) wherein A is selected from CX and N, B is selected from CY and N, R1 is selected from H and (C1-C6) alkyl, R2 is selected from H and (C1-C6) alkyl, X is selected from H, HO, C (O) NH2, NH2, Y is selected from H, HO, NH2, Br, Cl and F, Z is selected from H, HO, F, CONH2 and CN, and pharmaceutically acceptable salts and solvates thereof, under the conditions: when in the compound of formula (I), (Ia) or (Ib) A represents CX, then B represents CY, R1 is H or (C1-C6) alkyl, and R 2 is H or (C 1 -C 6) alkyl, and at least one of X, Y and Z must be OH, when in the compound of formula (I) A represents CX, then B represents CY, Y is H, Z is H, R 1 is H and R2 is H, and X then cannot be OH. The application contains 14 more claims. |