abstract |
A compound corresponding to general formula (I) in which A is selected from one or more groups X, Y and / or Z; X represents a methylene group which is optionally substituted by one or two C1-6 alkyl, C3-7 cycloalkyl or C3-7-cycloalkyl-C1-3-alkylene groups; Y represents either a C2-alkenylene group which is optionally substituted with one or two C1-6-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-3 -alkylene groups; or a C2-alkynylene group; Z represents a group of the formula: m represents an integer whose value is between 1 and 5; piq represents integers that are defined such that p + q is a number whose value is between 1 and 5; n represents an integer whose is a value between 1 and 7. R1 represents an R2 group optionally substituted by one or more R3 and / or R4 groups; R2 represented by pyridyl, pyridazinyl, pyrazinyl, triazinyl, furanyl, oxazolyl, pyrazolyl, isoxazolyl, thiazolyl, , 2-oxo-3,4-dihydroquinolinyl, 1-oxo-3,4-dihydroisoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, quinolinyl, naphthyridinyl, benzofuranyl, dihydrobenzofuranyl, benzothienyl, dihydrobenzothienyl, indolyl, benzyldazole, indolyl, indolyl, indolyl, indolyl, indolyl, indolyl ,, benzoxazolyl, benzothiazolyl, benzotriazolyl, benzoxadiazolyl, benzothiadiazolyl, pyrrolidine, imidazopyridyl, oxazolopyridyl, thiazolopyridyl, pyrazolopyridyl -6-alkoxy, hydroxyl, C1-6-thioalkyl, C1-6-fluoroalkyl, C1-6-fluoroalkoxy, C1-6-fluoro thioalkyl, NR5R6, NR5COR6, NR5CO2R6, NR5SO2R6, COR5, CO2R5, CONR5R6, SO2R5, SO2NR5R6, or -O- (C1-3-alkylene) -O- group. R4 represents a group selected from phenyl, phenyloxy, benzyloxy, naphthyl. a pyridyl, pyrimidyl, pyridazinyl or pyrazinyl group; whereby it is possible for the R4 group or groups to be substituted by one or more R3 groups which are identical or different from each other; R5 and R6 represent, independently of one another, a hydrogen atom or a C1-6 alkyl group or structure, with an atom wearing them, a ring selected from azetidine, pyrrolidine, piperidine, morpholine, thiomorpholine, azepine or piperazine rings, wherein this ring is optionally substituted with a C1-6 alkyl or benzyl group; R7 represents a hydrogen atom or a C1-6 alkyl group; R8 represents a hydrogen atom or a C1-6 alkyl, C3-7 cycloalkyl or C3-7 cycloalkyl-C1-3 alkylene group; in the form of a base or in the form of an acid addition salt, or a hydrate or solvate. The application contains 10 more claims. |