http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RS-51023-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_132aa5ddba376cda52c2bedb26765245 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 |
| filingDate | 2000-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3905c5a1f8216f0fe52921ec93daac81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df09c7e1b84b6de892449ce9c4bac2ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b38e5ffe4434cc6f792334e8d89715e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5c890fe31f36667205a93173036c82f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a95911689b48f0c11a15fdf589f0d33d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e430f85728c1ce35980fe9e5e7c71542 |
| publicationDate | 2010-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RS-51023-B |
| titleOfInvention | 6-ALKENYL, 6-ALKINYL AND 6-EPOXY-EPOTYLON DERIVATIVES, PROCEDURE FOR THEIR PRODUCTION AND THEIR USE IN PHARMACEUTICAL PREPARATIONS |
| abstract | An epothilone of a compound of formula I wherein R1a, R1b are the same or different and represent hydrogen; groups which may be substituted by 1-3 halogen atoms, C6-C12 aryl, which may optionally be substituted at one or more sites by halogen, OH, O-alkyl, CO2H, CO2-alkyl, -NH2, -NO2, -N3. -CN, C1-C20 alkyl, C1-C20 acyl, C1-C20 acyloxy groups or C7-C20 aralkyl, which may be optionally substituted at one or more sites by halogen, OH, O-alkyl, CO2H, CO2-alkyl, -NO2. -N3, -CN, C1-C20 alkyl, C1-C20 acyl, C1-C20 acyloxy groups, or taken together - (CH2) m-group with m = 1, 2, 3, 4 or 5 or - (CH2) - O- (CH2) -group; R 2a means hydrogen, C 1 -C 10 alkyl, which may optionally be perfluorinated or substituted with 1-5 halogen atoms, hydroxy groups, C 1 -C 4 alkoxy groups, optionally substituted C 6 -C 12 aryl groups which may be substituted with 1-3 halogen atoms. C6-C12 aryl, which may optionally be substituted at one or more sites by halogen, OH, O-alkyl, CO2H, CO2-alkyl, -NH2, -NO2, -N3, -CN, C1-C20 alkyl, C1-C20 acyl , C1-C20 acyloxy groups, or C7-C20 aralkyl, which may optionally be substituted at one or more sites by halogen, OH, O-alkyl, CO2H, CO2-alkyl, -NH2, -NO2, -N3, -CN, C1-C20 alkyl, C1-C20 acyl, C1-C20 acyloxy groups; R2b means - (CH2) rb-C≡C- (CH2) pb-R26b, - (CH2) rb-CH = CH- (CH2) pb-R26b, n means 0 to 5, ra, rb are the same or different and mean 0 to 4, so, pb are the same or different and mean 0 to 3, R3a means hydrogen or C1-C10 alkyl, which may optionally be perfluorinated or substituted with 1-5 halogens atoms, hydroxy groups, C1-C4 alkoxy groups, optionally substituted C6-C12 aryl groups which may be substituted by 1-3 halogen atoms, C6-C12 aryl, which may optionally be substituted at one or more sites by halogen, OH, O-alkyl, CO2H, CO2-alkyl, -NH2, -NO2, -N3, - CN, C, -C20 alkyl, C1-C20 acyl, C1-C20 acyloxy groups or C7-C20 aralkyl, which may optionally be substituted at one or more sites by halogen, OH, O-alkyl, CO2H, CO2-alkyl, -NH2. -NO2, -N3, -CN, C1-C20 alkyl, C1-C20 acyl, C1-C20 acyloxy groups, R3b means OH or OPG14 where PG14 is a protecting group, R14 means hydrogen, OR14a or Hal, where R14a is hydrogen, SO2- alkyl, SO2-aryl or SO2-aralkyl, R4 means hydrogen, C1-C10 alkyl, which may optionally be perfluorinated or substituted with 1-5 halogen atoms, hydroxy groups, C1-C4 alkoxy groups, optionally substituted C6-C12 aryl groups which may be substituted by 1-3 halogen atoms, C6-C12 aryl, which may optionally be substituted at one or more sites by halogen, OH, O-alkyl, CO2H, CO2-alkyl, -NH2, -NO2, -N3, - CN, C1-C20 alkyl, C1-C20 acyl, C1-C20 acyloxy groups or |
| priorityDate | 1999-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.