http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RS-50981-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcb35225a578542c5592310a91d18f18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65583 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-553 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 |
| filingDate | 2005-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_713197c2163b6386fe90e83bf6b78f50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da9a348f53cea2f5f27ed98e22f8e259 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ae7db3e46e656f53738cf355646fc75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca0a0247f20e584938acb55316c133f3 |
| publicationDate | 2010-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RS-50981-B |
| titleOfInvention | PHOSPHOINDOLES AS HIV INHIBITORS |
| abstract | Compound of Formula (A): or a pharmaceutically acceptable salt, N-oxide, quaternary amine, stereochemical isomer or tautomer thereof, wherein: X is substituted or unsubstituted phenyl; Y is O-alkyl; W is O; WITH; NH; N-N (R 2) (R 2); -N (R 2); N-OH or N-O-alkyl; R 2 each independently is H, OH; halogen; optionally substituted branched or non-branched alkyl; optionally substituted branched or non-branched alkenyl; optionally substituted branched or non-branched alkynyl; 3-14th carbocycle members; alkylheterocyclic; acyl; carboxamido; carbamoyl; alkoxy; optionally substituted aryl, optionally substituted aralkyl; optionally substituted alkylaryl; O-alkyl; O-alkenyl; O-alkynyl; O-alkaryl; O-aralkyl; O-carbocycle; O-heterocycle; O-aryl; CF 3; CN; S (O) n-R3; N (R 3) (R 3); NH-S (O) n-R3; NHC (= W) -aryl; NHC (= W) -alkyl; NHC (= W) heterocycle; CH2-S (O) n R 3; C (= W) R3; C (= W) NR3R3; C (alkyl) 2-S (O) n R 3; CH (alkyl) -S (O) n R 3; C (alkyl) 2-NH2; CH (alkyl) -N (alkyl) R 3; CR3R2-NR3R3; CH 2 N (alkyl) R 3; CH (alkyl) -NHR 3; C (alkyl) 2 -NHR 3; C (alkyl) 2-N (alkyl) R 3; CH2-C (= W) H; CH2-C (= W) alkyl; CR3R3a-C (= W) R3; A-R3; C (R3) 2-C (= W) R3; CH2-C (= W) H; CH2-C (= W) alkenyl; CH (alkenyl) -C (= W) H; A-S (O) R 3; CH (NH) -S (O) n R 3; or A-N (NH) R 3, wherein said optional substitution consists of one or more: substituted or unsubstituted heterocycle; C (= W) O-aryl; C (= W) O-alkyl; C (= W) NH 2: C (= W) NH-alkyl; C (= W) NH-aryl; C (= W) N-di-alkyl; C (= W) N (alkyl) -aryl; α-amino acids; α -amino ester; α-aminkarboksamid; β-amino acids; β-aminoester or β-amino-carboxamide; R3 each independently is H; OH; C1-6 alkyl; C2-6 alkenyl; C 2-6 alkynyl; alkoxy; CF 3; CN; amino; NR2R2; O-alkyl; O-alkenill; O-alkinill; C (R 2) (R 2) -S (O) n NH 2; C (R 2) (R 2) -S (O) n CF3; C (R2) (R2) -NH2; A-heterocycle; C (R2) (R2) -NR2R2; C (R 2) (R 2) -C (= W) R2; aryl; carbocyclic; heterocycle; cycloalkyl; alkaryl; alkylheterocyclic; aralkyl; or heterocyclylalkyl; each of which may be unsubstituted or substituted with one or more of the following, taken in any combination: halo; OH; OR 2; SR2; COOH; carboxylic acid ester; C (= W) R2; C (= W) OR 2; C (= W) OR3; C (= W) SR2; A-C (= W) NH2; C (= W) NR2R3; NR2R2; NR2R3; NR2-S (O) n R 3; NR2-C (= W) -C1-6 alkyl; S (O) n R 3; C1-6alkoxy; C 1-6 etioetar; amino acid residue; NH-A- (amino acid residue); C (= W) NH-A- (amino acid residue); and when said optional substitution contains a substituted heterocycle, then the substitution is selected from the group consisting of: C (= W) O-aryl; C (= W) O-alkyl; C (= W) NH2; C (= W) NH-aryl; C (= W) NH-alkyl; C (= W) N-di-alkyl; C (= W) N (alkyl) -aryl; α-amino acid; α -aminoester; α-amino-carboxamide; β-amino acid; β-aminoester; β-amino-carboxamide; halo; or cyano, taken alone or in any combination; n each independently, is 0, 1 or 2; A is a disubstituted spacer selected from the group consisting of: C 1-6 alkylene, branched or non-branched, optionally having one or more heteroatoms , aryl, ci |
| priorityDate | 2004-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.