| abstract |
Quinazoline derivatives of the general formula denoting Ra benzyl, 1-phenylethyl or 3-chloro-4-fluorophenyl group, Rb dimethylamino group and Rc cyclopropylmethoxy-, cyclobutyloxy-, cyclopentyloxy-, tetrahydrofuran-2-yl-oxy-, -yl-methoxy-, tetrahydrofuran-3-yl-methoxy-, tetrahydropyran-4-yl-oxy- or tetrahydropyran-4-yl-methoxy-group, with the exception of compound 4 - [(3-chloro-4-fluorophenyl) amino] -6 - {[4- (dimethylamino) -1-oxo-2-buten-1-yl] amino} -7-cyclopropylmethoxy-quinazoline, their tautomers, their stereoisomers and their salts. The application contains 9 more patent claims. |