| abstract |
1. Benzocycloheptenes of the general formula I in which R1 and R2 are independently of one hydrogen group, a hydroxy group, optionally substituted C1-C10-alkoxy group, optionally substituted C1-C10-alkanoyloxy group, or optionally substituted C7-C15-Aryloxy group, as well as SK for the side chain -ABZ, where A is a direct bond or oxygen atom, B is a straight or branched, optionally substituted alkylene, alkenylene or alkynyl group with up to 10 carbon atoms, Z is a group -D-SOx-EG, an amino group -NR7R6 or a substituent G, in which D is a direct bond or a group -NR (R4-), R3 straight or branched alkyl, alkenyl or alkynyl group having up to 10 carbon atoms as well as R4 straight or a branched, optionally substituted alkylene, alkenylene or alkynyl group of up to 10 carbon artoms, wherein the nitrogen atom may also be incorporated into a 4-7 membered ring system, x 0, 1 or 2, E straight or branched, in a given case of substance a tertiary alkylene, alkenylene or alkynylene group of up to 10 carbon atoms, G partially or fully fluorinated, straight or branched alkyl group of up to 5 carbon atoms, optionally substituted aryl or heteroaryl residue, carbamoyl residue -C (O) NR5R6 with R5 and R6 as defined by R7 and R8, a halogen or hydrogen atom, R7 and R8 independently of one another, a straight or branched hydrogen atom, optionally partially fluorinated alkyl, alkenyl or alkynyl radical having up to 14 carbon atoms which may be interrupted by up to three heteroatoms -O- and -S- and groups -NR9 -, in which R9 is a hydrogen atom or a C1-C3 alkyl moiety, optionally one or doubly substituted aryl or heteroaryl moiety, optionally one or doubly substituted C3- A C10-cycloalkyl residue, optionally one or doubly substituted C4-C15-cycloalkyl residue, optionally one or doubly substituted C7-C20-aralkyl residue, optionally one or two a substituted heteroaryl-C1-C8 alkyl residue or optionally an aminoalkyl residue. a biphenylene residue or a residue of the formula -C (O) R 10, in which R 10 may have the above meanings for R 7 or R 8, R 7 and R 8 having the nitrogen atom to which they are attached form a saturated or unsaturated heterocycle having 5 or 6 chain members , which in the present case contains one or two further heteroatoms, which are selected from nitrogen, oxygen and sulfur and optionally substituted, and in -ABZ, when A stands for oxygen atom and Z for G, G cannot be a hydrogen atom or the halogen atom, or when A stands for both the oxygen atom and Z for the amino group -NR7R8 to which R7 and R8 each represent a methyl group or together with the oxygen atom to form a pyrrolide |