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filingDate 2002-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9533e6f2de83d5197569b0882ace7006
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publicationDate 2007-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RS-40404-A
titleOfInvention INDOL-2-CARBOXAMIDES AS FACTOR INHIBITORS Xa
abstract The present invention relates to compounds of formula I wherein R 0, R 1, R 2, R 3, R 4, R 5, R 6, R 7, Q, V, G and M have the meanings indicated in the claims. The compounds of formula (I) are valuable pharmacologically active compounds. They have a strong antithrombotic effect and are suitable for, for example, the treatment and prophylaxis of cardiovascular disorders, such as thromboembolic diseases or restenosis. These are reversible inhibitors of factor Xa and / or factor VIIa of the blood clotting enzyme and can usually be used in conditions where undesirable activity of factor Xa and / or factor VIIa is present, or for treatment or prevention in which inhibition of factor Xa and / or factor VIIa. The present invention further relates to processes for the preparation of compounds of the formula I, to their use, and in particular as active ingredients in medicaments or pharmaceutical compositions containing them.
priorityDate 2001-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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