| abstract |
Multiparticle pantoprazole sodium that avoids sticking to nasogastric tubes and feeding tubes has been described. The multiparticulate pantoprazole has a spheroidal nucleus of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant and a disintegrant; a sublayer comprising hydroxypropyl methylcellulose (hypromellose) and water, an entero coating on the sublayer and a final insulating coating over the entero coating, consisting of hydroxypropyl methylcellulose (hypromellose) and water. |