abstract |
The invention encompasses the preparation of an antacid agent based on a thixotropic stable aluminum phosphate-based suspension, which is essentially a buffer, and because of this property protects the gastric mucosa from the aggressive action of acid, prevents the occurrence of anacidity. The essence of our invention is that the preparation process provides that in acidic solution of reactants (aluminum and phosphate reactive ions), APTS is synthesized and formed at the target and controlled pH by the addition of an aqueous hydroxide solution. This avoids the formation of inhomogeneous and unstable gel structures due to the deposition of aluminum phosphate at different pH values, the formation of (-Al-O) n-Al- polymerization products, when aluminum hydroxide is deposited in addition to the amorphous aluminum phosphate. |