http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-97963-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69b61dda31f1fd520ae4f9192cfac897 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
filingDate | 1987-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80c762e6526d43cec7f9ac2950b5795d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cba1aa24ca28f75c6e14fbb33bc7fcb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb8f6baf4db198da718319bae23c2234 |
publicationDate | 1989-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RO-97963-B1 |
titleOfInvention | PROCESS FOR OBTAINING Erythromycin ETHYLSUCCIN |
abstract | The present invention relates to a process for the preparation of erythromycin ethylsuccinate by acylating the solution of erythromycin in methylene chloride or chloroform with monoethyl succinyl chloride as the solution in the solvents mentioned above in the presence of sodium bicarbonate at a ratio of 2.5 ... 3.5 moles / mole of acid chloride at 0-27 ° C, the reaction product is isolated by filtration of the resultant precipitate which is then suspended in cold water in an amount of 1 g to 15-30 ml, filter the slurry and dry under reduced pressure at 20-30 ° C. The process is simple and allows the use of erythromycin ethylsuccinate for pharmaceutical use. |
priorityDate | 1987-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.