http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-83707-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-08 |
| filingDate | 1982-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2de0b30adf098e024430eec63c525d7 |
| publicationDate | 1984-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RO-83707-B |
| titleOfInvention | PROCEDURE FOR PREPARATION OF CLORMALTY ESTERS OF ANY DERIVATIVES OF PENYCLANIC ACID |
| abstract | The invention relates to a process for the preparation of chloromethyl esters of penicillanic acid derivatives of the general formula I: (where n is 0 or 2) and R is hydrogen, (see form in the appendix) wherein R1 is azido, amino, carbobenzyloxyamino or 1-methoxycarbonylpropen-2-ylamino and R2 is hydrogen or hydroxy with the proviso that when n is 2, R is hydrogen consisting of a compound of general formula II: wherein n and R are as defined above and R 3 is C 1 -C 4 alkyl is reacted with a chloromethylating agent selected from bromochloromethane and iodochloromethane at a temperature of between -20 and 25 ° C, the molar ratio between the tetraalkylammonium salt of formula II and the chloromethylating agent being 1: 1, preferably using an excess of the chloromethylating agent. |
| priorityDate | 1981-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.