http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-81937-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0ff16e899ce32685c9600075c1cc21 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 |
| filingDate | 1979-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c88c885b5f9ad5dea32a182d22061e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b84d6d0a10a5d14e7af76eb0ebe4c73 |
| publicationDate | 1983-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RO-81937-B |
| titleOfInvention | PROCESS FOR THE PREPARATION OF DERIVATIVES OF ACID 7 BETA-AMINOTIAZOLE-ACETAMIDO-3-CEFEM-4-CARBOXYLIC ACID |
| abstract | The invention relates to a process for the preparation of 7-beta-aminothiazolylacetamido-3-cephem-4-carboxylic acid derivatives of the general formula I wherein A represents a methylene group optionally substituted with an amino, hydroxyimino, R 1 represents hydrogen, pivaloyloxymethyl, p-nitrobenzyl or diphenylmethyl, and R 2 represents hydrogen or a methoxy group, wherein a compound of the general formula II wherein X represents a halogen atom and R 1, R 2 and A are as defined above, is condensed with thiourea or a salt thereof at room temperature using dioxane as the solvent, whereupon when R 1 represents a carboxy-protecting group it is replaced by hydrogen by methods in themselves known and / or if desired, the compound obtained is converted into a pharmaceutically acceptable salt thereof. |
| priorityDate | 1978-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.