http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-135359-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ded252b2943e4007e87dbf7d448de74 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 |
filingDate | 2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00012d61cea59df8734014cdf31c4022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c804e467d8ef1512ad7d5309b72e8538 |
publicationDate | 2021-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RO-135359-A2 |
titleOfInvention | NEW ANALOGS 1'-HOMOCARBONUCLEOSIDES WITH A BICYCLE [2.2.1] HEPTANIC RIGIDIZED FRAGMENT AND AS A NUCLEO-BASED 2-AMINOPURINE SUBSTITUTED IN POSITION 6 |
abstract | The invention relates to optically active (+) -, (-) - or racemic 1'-homocarbacyclonucleoside derivatives with viral and / or antitumor action and methods for obtaining them. The derivatives according to the invention have the general formula I, containing as heterocyclic base guanine, guanine substituted with an alkyl group to the hydroxyl group, 2-aminopurine substituted in position 6 with a chlorine atom, a substituted or unsubstituted amino group, and as a glycosidic residue a specific functionalized heptane bicyclo [2.2.1] radical bound to the N9 nitrogen atom of the nucleobase via the exocyclic methylene group. |
priorityDate | 2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 510.