http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-134523-A0
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_073b8aa73a31e2526f2d4d028363c4bb |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2020-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0bb9549243e3de630fc59396bd866d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7e35aae7b4bf5313fb9f1c5a9437b83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9b0e0b19a3edd501f42f7d7da53e8b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f96cdad946b3b68e02c282165a80fba7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3faf28dcce927703c5bf0950b0d133bb |
publicationDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RO-134523-A0 |
titleOfInvention | RATIONAL SCREENING METHOD OF COMPOUNDS CAPABLE OF TARGETING THE INVASIVE PHENOTYPE OF TUMOR CELLS ISOLATED FROM BREAST CANCER PATIENTS |
abstract | The invention relates to a rational method of screening compounds capable of targeting the invasive phenotype of tumor cells isolated from breast cancer patients. The method, according to the invention, consists in determining the tumor invasive phenotype specific to each patient by using microfluidic devices with channels of 10 ... 12 microns, identifying the transcriptomic signature associated with the phenotype, which is used to interrogate molecular prediction software for rational identification. of a set of compounds capable of modulating the migratory phenotype of tumor cells isolated from breast cancer patients. |
priorityDate | 2020-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 595.