http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-132541-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c1496ee22f9a7f75e0dc30e6633e01d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 |
| filingDate | 2016-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e5b0ca7a873585e0b5bd7f34c05e6dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6a1c4ac3b43334eca289201491c9a5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cd8dae78f20c2f6193ab457caf0b367 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eee64872c2625f5456bb41399e2b910 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f74d102f947bc142dc42e44a2ef8245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3b97b30334044670f672f4cc21d02d9 |
| publicationDate | 2018-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RO-132541-A2 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF A BOTTOM STRUCTURE WITH BIOMEDICAL APPLICATIONS |
| abstract | The invention relates to a process for obtaining a crosslinked structure with biomedical applications. The process according to the invention consists in the synthesis of 1,4-dioxane copolymerization of the itaconic anhydride copolymer and 3,9-divinyl-2,4,8,10-tetraoxaspiro [5.5] undecan, in molar ratios of 1: 0.5 and 1: 2, with the radical initiator 2,2'-azobis (isobutyronitrile) added in three steps at 75 ° C for 17 hours with stirring of 250 rot / min, resulting in the solution copolymer precipitated in anhydrous diethyl ether, separated and dried at 30 ° C, then mixed in a 20% strength solution in 1,4-dioxane with 1% hyaluronic acid in water , at ambient temperature 22 ° C for 24 hours, in steady state, dialysis and lyophilization, resulting in a double-sensing gel structure with temperature and pH. |
| priorityDate | 2016-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.