| abstract |
The invention relates to polymeric granules with hypericin and to a process for their preparation, used for food supplements. The granules according to the invention have the ability to absorb the hypericin Qde 0.25 ... 0.66 mg / g and the chlorophyll Qde 0.0007 ... 0.01 mg / g, the selectivity of the uptake of hypericin versus chlorophyll where 7.3 ... 159.9 and an average diameter of 24.3 ... 133.7 μm. The process according to the invention consists in the suspension polymerization of vinyl monomers in admixture with a bifunctional monomer, crosslinking, the hypericin imprinting being carried out with alcoholic solution of hypericin or a St John's Wort hypericin extract, and then creating the centers of molecular recognition with ethyl alcohol or with sodium hydroxide solution, followed by neutralization. |