http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-126835-A0
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f94cd9fb0a1b30beeaf0a94369350ef |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
| filingDate | 2011-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d524df9930a733ce1f744f6d10581754 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_005da86c9fda8b57b8971423ebfac54e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2cfc06e12747b1826a90237adc28969 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d0ca11331eb2fc1c10962f98e627507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b9f7a9a8c21366029ab0c16d1ddb7c5 |
| publicationDate | 2011-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RO-126835-A0 |
| titleOfInvention | BIOABASORABLE COMPOSITE MATRIX BIOMATERIAL "PROBIOS-IMPLANT" BIOCOMPATIBLE SUPPORT AND IMPLANT PROCESSES FOR CHARACTERIZATION |
| abstract | BACKGROUND OF THE INVENTION The present invention relates to a bioabsorbable composite bio-material having the role of a biocompatible support for in vitro culture cells, as an implant for the regeneration of articular cartilage. The product according to the invention is a composite composed of collagen, glycosaminoglycans, growth factor, porous appearance and three-dimensional configuration in dry lyophilized state or hydrogel. The process according to the invention involves mixing, in a capsulated planetary mixer, type I collagen and a composite solution consisting of one liter of chondroitin-6-sulfate solution with a concentration of 2.5% for 60 minutes at a temperature at 10 ° C and 1 torr pressure, then the solubilising factor is added to the same buffer, and stirring is continued for about 2 hours at 15 ° C, and the resulting hydrogel is lyophilized, then decoupled to the desired size, conditioned and is sterilized against UV radiation or gamma radiation, keeping it dry and away from light. |
| priorityDate | 2011-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.