http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-126039-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95d0fca9aa163aebed70613c1063cc49 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate | 2009-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeddc1f0fbbe6d5f1ea717b3f69798ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc752db050b3d5f90be73ceb2a22fbb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7143ef314629e2969af5e7ef897deecd |
| publicationDate | 2011-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RO-126039-A2 |
| titleOfInvention | PROCEDURE TO EXTEND ANTIMICROBIAL ACTIVITY OF GENTAMICINE |
| abstract | The invention relates to a process for enhancing the antimicrobial activity of gentamicin. According to the invention, the process consists in selectively removing gentamicin C, the lowest biological activity component, from the resulting solution resulting from the biosynthesis by the reactive 1: 1 extract of gentamicin-containing aqueous solution adjusted to pH = 8 with dichloromethane containing 1 to 6% of di (2-ethylhexyl) phosphoric acid at 25 ° C with vigorous stirring for 1 minute followed by separation and re-extraction of gentamicines C and C in the 1: 1 organic phase with 0.2 ... 1.1% sulfuric acid at 25 ° C, under vigorous stirring for 1 min. |
| priorityDate | 2009-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.