| abstract |
The invention relates to pyrazole-thiazine and thiazole-thiazine derivatives represented by the general formula (1) or (2): to pharmaceutical compositions containing them and their use in the treatment of disorders such as major depression, anxiety- posttraumatic stress, supranuclear palsy and eating disorders, as well as the treatment of neurological diseases, colon hypersensitivity, cardiovascular diseases or diseases caused by heart diseases associated with pathophysiological and stress disorders. |