| abstract |
The invention relates to analogous derivatives of vitamin D, having the general formula I: wherein Q represents a C1 -C8 hydrocarbyl diradical, R represents hydrogen or C1 -C6 hydrocarbyl, or double bonds R taken together with the carbon atom bearing the hydroxy group, may form a C3-C8 carbocyclic ring; to a process for their preparation, to intermediates used in the preparation of vitamin D derivatives, to pharmaceutical compositions containing these compounds, and to the use of such derivatives in the treatment or prophylaxis of diseases characterized by abnormal cell differentiation and / or abnormal proliferation of cells, such as psoriasis and cancer. |