| abstract |
The invention relates to a method of treatment for the inhibition of smooth muscle vascular cell migration, which comprises administering to humans or other mammals a dose of 0.1 ... 1000 mg per day, preferably 50 ... 200 mg per day, once to three times a day, a compound of formula (I) wherein R 1 and R 2 independently represent a hydrogen atom, a methyl group, a (a) or (b) group wherein : Ar is optionally a substituted phenyl group, R2 is a pyrrolidino group, a hexamethyleneimino group or a piperidino group, or pharmaceutically acceptable salts and solvates thereof. |