abstract |
The present invention relates to a process for the preparation of (S) -2-tert-butylcarboxamidpiperazine, intermediate compound for the preparation of HIV protease inhibitors (human immunodeficiency virus), especially used in the preparation of N- (2 (R) -hydroxy -1- (3-pyridylmethyl) -2 (S) -N '- (tert -butylcarboxamido) piperazinyl) pentanamide (L-735524) or pharmaceutically acceptable salts. |