| abstract |
The invention relates to a method of antagonizing or blocking the calcium channel which consists in administering to a warm-blooded animal, 0.1 ... 1000 mg / day, from 1 to 3 times per day on a compound of formula (I): or a pharmaceutically acceptable salt of this compound, wherein: R 1 and R 3 are independently hydrogen, C 1 -C 4 alkyl, -CO- (C 1 -C 6 alkyl) or -CH 2 Ar, -CO-Ar, where Ar is phenyl or substituted phenyl, R2 is selected from the group consisting of pyrrolidine, hexamethyleneimine and piperidine, in order to treat cardiac dysfunctions, cerebral disorders, renal and intestinal disorders, and hypertension. |