http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RO-115954-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3899a93c972ce60b070fca823112248 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
| filingDate | 1993-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f8a6ad197adb9a628ca7dcdfd784213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_534add5b9bbb977ddb237176ac02fc3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_222a92be4d6bec172b7e9f29ea0c38d4 |
| publicationDate | 2000-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RO-115954-B1 |
| titleOfInvention | CHINOLINE DERIVATIVES, COMPOSITION WHICH CONTAIN, AND TREATMENT METHOD |
| abstract | The present invention relates to quinoline derivatives, compositions containing them and the method of treatment, said derivatives having antagonistic activity towards leukotrienes as well as leukotriene biosynthesis inhibiting activity are recommended for the treatment of angina, cerebral spasm, glomerular nephritis, hepatitis , endotoxemia, uveitis and rejection of allografts. The quinoline derivatives according to the invention have the structural formula (I): wherein R1 is 6-fluoro or 6,7-difluor or a pharmaceutically acceptable salt thereof. The composition of the present invention consists of a therapeutically effective amount of a compound as defined in formula (I), optionally a second active ingredient and a pharmaceutically acceptable carrier. The method of treatment according to the invention consists in administering a therapeutically effective amount of a compound of structural formula (I) to a mammal in need of such treatment. |
| priorityDate | 1992-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 387.