| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ea17ba87480b776cce77451f86b25bb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-06 |
| filingDate |
1995-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94b42183691f6f4e02ad6fbd2cb5a3fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1a5cb22ab6995f3d42ff93eb5b3629d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd1ce7105a4dfaa7b96678fa505beda |
| publicationDate |
2000-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RO-115875-B1 |
| titleOfInvention |
TAX DERIVATIVES, PROCESS FOR PREPARING THEM, INTERMEDIATE FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITION CONTAINING |
| abstract |
The present invention relates to novel taxane derivatives of general formula (I): to a process for their preparation by oxidation and stereospecific reduction of 10-deacetylbaccatin III and subsequent esterification with a substituted isoserine chain, to an intermediate for their preparation and to the pharmaceutical composition containing it. The derivatives according to the invention show cytotoxic and antitumor activity and can be formulated accordingly for administration by injection and / or oral administration. |
| priorityDate |
1994-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |