http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-92056-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77f52cdaaeebdd6c2251c198243ef07e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00 |
filingDate | 1989-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11f349ae147d7da9a48ed5b57a4b2e65 |
publicationDate | 1990-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PT-92056-A |
titleOfInvention | PROCESS FOR THE COMPOSITION AND USE OF PEPTIDES CPF |
abstract | Compsn. comprises a CPF peptide (I) (or its biologically active analogue or deriv.) and a carrier. Also claimed is a process for inhibiting growth of a target cell by admin. of (I). Pref. (I) has following basic structure (x): R1 = a hydrophobic aminoacid; R2 = basic hydrophilic or hydrophilic-aminoacid; R3 = a basic hydrophilic aminoacid; R4 = a hydrophobic or neutral hydrophilic aminoacid; R5 = a basic or neutral hydrophilic aminoacid. (I) pref. includes structure Y-X- (i) or -X-Z- (ii): Y = R5, R2-R5-, R1-R2-R5- or R2-R1-R2-R5; Z = R1,R1-R1-, R1-R1-R4-, R1-R1-R4-R4-, R1-R1-R4-R4-R6-, R1-R1-R4-R6-Gln or R1-R1-R4-R4-R6-Gln-Gln; R6 = proline or a hydrophobic aminoacid. Prefd. peptides are of formula (Y-)a-X-(Z)b (Ia): a = 0 or 1; b = 0 or 1. (I) are known (see eg Richter K., Egger R., and Kreil (1986) J. Biol. Chem 261, 3676-3680). |
priorityDate | 1988-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458397385 |
Total number of triples: 11.