http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-88504-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 |
filingDate | 1988-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8101e46de1b76a9b6281859d68f71a6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02f1f4f9d4d095893f388b69c4bbc5f4 |
publicationDate | 1992-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PT-88504-B |
titleOfInvention | PROCESS FOR THE PREPARATION OF HALOALQUIL-TIAZOLES |
abstract | A process for the preparation of a compound of the formula <CHEM> wherein R<1> is hydrogen or (C1-C4)alkyl, X is chloro or bromo and A represents a 6 membered carbocylic aromatic or a 5 or 6 membered heterocyclic ring which is optionally substituted by one of iodo or trifluoromethylthio, or one or two of fluoro, chloro, bromo, (C1-C4)alkyl, (C1-C4)alkoxy, (C1-C4)alkylthio, (C1-C4)alkylsulfinyl, (C1-C4)alkylsulfonyl, or trifluoromethyl, comprising reacting haloacetonitrile with a compound of the formula <CHEM> wherein A is as defined above or a hydrohalide salt thereof. The compounds of the formula (I) are useful intermediates in the preparation of heterocyclic oxophthalazinyl acetic acids having aldose reductase inhibitory activity. Some of the compounds of the formula (I) are novel, and these also form a part of the invention. |
priorityDate | 1987-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.