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filingDate 1988-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aedc744329e13a653c32f238027562d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e53aa91819c88a1a297438981fc17652
publicationDate 1992-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PT-86902-B
titleOfInvention PROCESS FOR THE PREPARATION OF DERIVATIVES 23-DESOXY-27-HALO (CHLORO OR BROMINE) OF COMPOUNDS LL-F28249
abstract The present invention relates to novel derivatives of LL-F28249 compounds. These LL-F28249 compounds preferably are derived via a controlled microbiological fermentation of Streptomyces cyaneogriseus subspecies noncyanogenus having deposit accession number NRRL 15773. The 23-deoxy-27-halo(chloro or bromo) derivatives have the 23-hydroxy group of the LL-F28249 compounds replaced by hydrogen and a halogen such as chlorine or bromine in the 27-position with the double bond shifted to the 26,26'-position. The novel derivatives of the present invention possess activity as anthelmintic, ectoparasitic, insecticidal, acaricidal and nematicidal agents and are useful in areas of human and animal health and in agricultural crops. Compositions containing the present compounds also are presented herein.
priorityDate 1987-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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