http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-86882-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-04 |
| filingDate | 1988-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d45cdb997aeada208aec991434e408c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_092df6aa623d6944aef705423e92acf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de7053e567bc1395b138e429c77ce553 |
| publicationDate | 1990-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PT-86882-A |
| titleOfInvention | PROCESS FOR THE PREPARATION OF DISSACIRED DERIVATIVES |
| abstract | Amino-substd. disaccharide phosphate derivs. of formula (I) and salts are new (where R = phosphous gp., ZR6 or CH(Z1R6)(Z2R6); Z, Z1, Z2 = 1-6C alkylene; R6 = carboxyl or phosphonoxy gp.; R1-4 = -COR7, -COZ3R8, -CO(CH2)n1-CHQ-NQ1-COR7, -CO(CH2)n1-CHQ-NQ1-COZ3R8, -CO(CH2)n2-O-COR7, -CO(CH2)n2-O-COZ3R8, -CO(CH2)n2-COR7, -CO(CH2)n2-COZ3R8, -CO(CH2)n2-CO(CH2)n3-NQ1-COR7 or -CO(CH2)n2-CO(CH2)n3-NQ1-COZ3R8; R7 = 1-30C alkyl, opt. substd. by OH gp(s).; Z3 = 1-9C alkylene; R8 = 3-12C cycloalkyl, opt. substd. by OH gp(s).; Q = H, 1-6C alkyl, -CONH2, -COOH or -CH2OH; Q1 = H or 1-20C alkyl; n1 = 0 or 1-20; n2, n3 = 1-20; R5 = H, phosphous or -CO(CH2)mCOOH; and m = 0 or 1-6; but excluding cpds. where R = phosphous; R5 = H; and R1-4 = -COR7.) USE/ADVANTAGE : (I) are useful as antitumour agents, and have lower toxicity and activity equal to or higher than that of known derivs. of natural lipid A. (Provisional Basic previously advised in week 8907). |
| priorityDate | 1988-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.