http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-86636-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f88f84fc279fe5d0b9b5ec3c88c2e2b2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-04 |
filingDate | 1988-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89a023ba162878a00f2afde2d5a7534d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3360655892fdab7881fd718898276326 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29baa1ae8bc8e0bfe076d5a354d7825e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_884aa11d82ffd69c1f6efbedb870f5fe |
publicationDate | 1992-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PT-86636-B |
titleOfInvention | PROCESS FOR THE PREPARATION OF AZETIDINE AND NEW INTERMEDIATE COMPOUNDS OF THIS SYNSTATE |
abstract | A novel process is described for preparing azetidine and 2 or 3 methyl and ethyl azetidine free bases by reacting primary arylmethylamine having suitable bulk providing substituents attached to the methyl carbon and an appropriate propane derivative having leaving groups in the one and three position in hot organic solvent containing a non-nucleophilic base and an amount of water sufficient to promote azetidine ring formation to give N-protected-azetidines and deprotecting by hydrogenolysis under acidic conditions to give an acid salt of the azetidines and thereafter flashing off vaporized azetidine from a hot, agitated strong base solution or slurry and condensing to give the liquid azetidine free bases. |
priorityDate | 1987-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.