| abstract |
Substituted alpha -amino acids useful for treating epilepsy, disorders associated with excess GH or LH secretion, anxiety, schizophrenia, depression, CNS degenerative disorders, cerebral hypoxic conditions and stress-related psychiatric disorders: are alpha -amino- alpha -(3-alkylphenyl) alkyl-ethanoic acids or esters or amides thereof, in which the 3-alkyl moiety bears a phosphorus oxo acid group or an ester thereof, wherein phosphorus is attached directly to the alkyl moiety, or salts thereof. The compounds may have the formula:- <IMAGE> wherein R1 R1, R2, R3, Y, m and n have certain defined meanings, Y being linked via a phosphorus atom. |