http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-86000-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba090c867801ab7bccb082f1b694ad25 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-04 |
| filingDate | 1987-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00222a4e7dfb58eb330dcc5811d7581e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7b2dab0bbe198c993a2ced103058fe5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c533d3b430f3e385b3a612592f135bdd |
| publicationDate | 1990-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PT-86000-B |
| titleOfInvention | SUBSTITUTED TETRA-HYDRO-ISOKINOLINES PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| abstract | The invention provides compounds of the formula (I): <CHEM> and salts thereof; wherein A is a group NR<3>SO2 or SO2NR<3>; B is an acyclic hydrocarbon group having from one to six linear carbon atoms, provided that the carbon atom attached to the nitrogen atom is saturated; Y is CO2H or a group hydrolysable to CO2H; R<1> is phenyl optionally substituted by one or more substituents chosen from the group comp rising halogen, C 1-4alkyl, C 1-6acyl, C 1-4alkoxy, nitro and trifluoromethyl; R<2> is hydrogen or one or more C 1-4alkyl substituents located at the 1, 3 and 4 positions of the isoquinoline ring; and R<3> is hydrogen or C 1-6alkyl. Also disclosed are pharmaceutical compositions containing the compounds, methods for making them and the use of the compounds as thromboxane A2 antagonists. |
| priorityDate | 1986-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.