abstract |
There are described compounds of formula I, <CHEM> in which R1 to R8 have a variety of significances, including alkoxy, hydrogen, alkyl, n is 0 or l, R11 is hydrogen, phenyl, alkenyl, or alkyl optionally substituted by phenyl, R9 and R10 have a variety of significances, including cycloalkyl, alkyl, or may form a ring with the nitrogen atom to which they are attached, and certain provisos. Processes for making the compounds and pharmaceutical formulations containing them, eg for the treatment of conditions including excess gastric acidd secretion, are also described. |