http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-80758-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate | 1985-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43fd99e27a21df02459f00cf98428187 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd81cfc163d1481b95762060a37d1a66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6680c02e8d00972863191d32697871ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b71f1c8d287c73ca9b388867b277e07 |
| publicationDate | 1985-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PT-80758-A |
| titleOfInvention | Method for preparing tumor necrosis factor |
| abstract | Prepn. of tumour necrosis factor (TNF) from mixts. with other proteins comprises adsorption onto a hydrophobic substance (A) or anion-exchange resin of uniform particle size, then eluting. (A) is esp. controlled pore glass or polystyrene beads (pref. eluted with ethylene glycol) and the ion-exchanger is esp. quat. ammonium substd. crosslinked polystyrene. Homogeneous TNF is new; esp. it is free of lymphotoxin and has activity about 10 million units/mg of protein. Also new are mutant forms of TNF having one or more amino acids substd., deleted or inserted; DNA coding for these mutant forms and cells transformed with this DNA. |
| priorityDate | 1984-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.