http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-79507-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34c5de6469fe454787f9f22329565a67 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate | 1984-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1986-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PT-79507-B |
| titleOfInvention | Supressive factor of allergy |
| abstract | Hybridoma cell line characterised by prodn. of suppressive factor by allergy (SFA) is new. It is esp. line 1C1. Pref. the cell line comprises a fusion of cells from Jurkat human T-cell leukaemia and SFA-producing human peripheral blood lymphocytes. The SFA or a SFA-contg. supernatant is at least 50% effective in inhibiting FcRe expression at dilutions exceeding 1:1000. The hybridoma cell line comprises a mRNA molecule comprising a RNA sequence coding for SFA. SFA may be detected by (a) treating a culture of mouse splenocytes with a measured amount of soluble monoclonal antibody to T-lymphocytes; (b) adding the test sample; (c) adding mouse anti-2,4-dinitrophenyl; and (d) determng. the FcRe positive cells by a rosette-forming assay, with comparison with control cultures free from SFA. |
| priorityDate | 1984-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.