http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-77773-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a5173a7d063a9f70ca7b5e86fc23863 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-08 |
| filingDate | 1983-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1986-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PT-77773-B |
| titleOfInvention | Process for the preparation of new 5-(aryl-aliphatic)-3-lower alquylisoxazoles and isomeres thereof |
| abstract | Compounds of the Formulas I or II (herein) wherein R is alkyl, X is 0 or CH 2 , n is an integer from 4 to 8, and Ar is phenyl or substituted phenyl, useful as antiviral agents especially against picornaviruses. Said compounds are prepared by:n a) reacting an alkali metal derivative of 3-R-5-methylisoxazole with a compound of the formula Hal-(CH 2 ) n -X-AR' where Hal is bromine or iodine, and Ar' is phenyl or phenyl substituted by one or two halogen, lower-alkyl, lower-alkoxy, nitro or cyano substituents to produce a compound of the Formula (I) wherein Ar is phenyl or phenyl substituted by one or two substituents which are halogen, lower-alkyl, lower-alkoxy, cyano or tertiary-butyloxy-carbonyl; or b) reacting a compound of the formulan where Hal is bromine or iodine, with an alkali metal salt of a compound of the formulan where Ar' has the meaning given above, followed by optimal conversions of the phenyl substituents of Ar. |
| priorityDate | 1982-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.