http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-76848-A

Outgoing Links

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D-
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filingDate 1983-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1983-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PT-76848-A
titleOfInvention Process for preparing anti-coagulants of the 4-hydroxycoumarin type and rodenticidal compositions comprising such anti-coagulants
abstract Cpds. of formula (I) having blood anticoagulant properties are new. In (I) Z is halogen; n is 0-2; R4 is (1) phenylene attached directly or indirectly to the tetralin ring and having in the p-posn. an electron-withdrawing atom or gp. whose rotational vol. does not exceed that of a Ph gp. and forming with the phenylene a polarisable structure; or (2) 4-pyridinyl, p-(4-pyridinyl)phenyl or p-(4-pyridinyloxy)phenyl; or (3) phenylene attached directly to the tetralin ring and p-substd. by substd. furanyl or thiophenyl attached directly or through O and/or CH2, the furanyl or thiophenyl having an electron-withdrawing atom or gp. as substituent in a posn. to form with the furanyl or thiophenyl gp. a polymerisable structure, the atom or gp. having a rotational vol. that does not exceed that of a Ph gp. Cpds. (I) are blood anticoagulants and some cpds. are more active than Bradifacoum and Difenacoum; and so they are esp. effective as rodenticides.
priorityDate 1983-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 20.