http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-68654-A

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1cd6051bf69f25a0652ded4e4edac31
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-00
filingDate 1978-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PT-68654-A
titleOfInvention A process for the production of new pyranoquinolinone derivatives
abstract Pyranoquinolines of formula (I) and their pharmaceutically acceptable derivs. are new. In the formula, two of R5, R6, R7 and R8 on adjacent C complete -CO.CH=CE.O-, while the other 2 are H, halo, OH, alkyl, alkenyl, alkoxy or NR1R2; Rg is H, alkyl, alkenyl or phenalkyl; E is COOH, 5-tetrazolyl or (N-tetrazol-5-yl) carboxamido; R1 and R2 are H or alkyl. (I) are made e.g. by cyclising a benzopyran substd. by -NRg.CH(COOH)=CHCOOH. (I) inhibit the release and/or effect of mediators formed by certain antigen-antibody reactions so are useful e.g. in treating asthma, bronchitis, coughs, conditions associated with excessive mucus prodn. (hay fever), trachoma, food, allergy, eczema etc. The usual human dose is 1-600mg/day.
priorityDate 1978-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 16.