http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-68654-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1cd6051bf69f25a0652ded4e4edac31 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-00 |
filingDate | 1978-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1978-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PT-68654-A |
titleOfInvention | A process for the production of new pyranoquinolinone derivatives |
abstract | Pyranoquinolines of formula (I) and their pharmaceutically acceptable derivs. are new. In the formula, two of R5, R6, R7 and R8 on adjacent C complete -CO.CH=CE.O-, while the other 2 are H, halo, OH, alkyl, alkenyl, alkoxy or NR1R2; Rg is H, alkyl, alkenyl or phenalkyl; E is COOH, 5-tetrazolyl or (N-tetrazol-5-yl) carboxamido; R1 and R2 are H or alkyl. (I) are made e.g. by cyclising a benzopyran substd. by -NRg.CH(COOH)=CHCOOH. (I) inhibit the release and/or effect of mediators formed by certain antigen-antibody reactions so are useful e.g. in treating asthma, bronchitis, coughs, conditions associated with excessive mucus prodn. (hay fever), trachoma, food, allergy, eczema etc. The usual human dose is 1-600mg/day. |
priorityDate | 1978-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.