http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-67452-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a899eba0e35112cc25b4aa1b0b7fda90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D461-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-20 |
| filingDate | 1977-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1978-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PT-67452-A |
| titleOfInvention | PROCESS FOR THE PREPARATION OF NEW ORGANIC COMPOUNDS WITH PHARMACEUTICAL EFFECT |
| abstract | 10-Bromovincamine (I) and its acid addn. salts and 10-bormo-epivincamine are new, in optically active or racemic form. (I) is a psychostimulant and agent for increasing vigilance. It may be used for treating cerebral insuficciency at a daily dose of 10-50 mg. In an example, (3S, 14S, 16S)-(I) was prepd. from vincadifformine via the novel intermediates 15-bromo-vincadifformine and methyl 5-bromo-1,2-didehydro-3-hydroxy-aspidospermidine-3-carboxylate 9-oxide by bromination, reaction with m-chloroperbenzoic acid and heating in presence of PPh3 and acetic acid. |
| priorityDate | 1977-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.