http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PT-109860-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c83971dae1af3500e88babcc816556a3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-00 |
| filingDate | 2017-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42bf7950f2776ebf9ca026b26b91531e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62c6a53aed51215c67f06fb00b866a89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f20bfec1d6562c70ab434ed1efac7fc6 |
| publicationDate | 2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PT-109860-A |
| titleOfInvention | NEW N- (1,2,3-Triazolmethyl) -3-Hydroxy-3-aryloxydolides Non-rhythmic cytotoxic chirals |
| abstract | The invention relates to the preparation of novel N- (1,2,3-Triazolmethyl) -3-Hydroxy-3-aryloxydols from appropriate isatin precursors using chiral catalysts based on transition metal which have a demonstration of intrinsic resistance. POWERFUL AGAINST TUMOR CELLS. THESE N- (1,2,3-Triazolmethyl) -3-HYDROXI-3-ARYLOXYDOLLES COMPOUNDS OF THE FORMULA (I) ARE OBTAINED IN AN ENHANICOMICALLY ENRICHED OR PURPOSE FROM FORMULA (2) PRECURSORS EFFICIENT ARILATION USING Boron-derived ARILO REAGENTS AND A CHIRAL CATALYST BASED ON TRANSITION METAL UNDER SOFT REACTION CONDITIONS. THIS APPLICATION DESCRIBES THE PREPARATION OF N- (1,2,3-Triazoylmethyl) -3-Hydroxy-3-aryloxydol compounds of formula (2) which are inhibitory potents of certain tumor cell lines. |
| priorityDate | 2017-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.